Boswellic acid sensitizes gastric cancer cells to Cisplatin-induced apoptosis via p53-mediated pathway

• Glavni autori: Shadia Al-Bahlani (Autor), Ikram A. Burney (Autor), Buthaina Al-Dhahli (Autor), Safiya Al-Kharusi (Autor), Fakhra Al-Kharousi (Autor), Amani Al-Kalbani (Autor), Ikhlas Ahmed (Autor)
• Format: Knjiga
• Izdano: BMC, 2020-09-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Background Cisplatin (CDDP) is an effective anticancer drug for Gastric cancer (GC) that induces apoptosis by altering pro- (p53) and anti-apoptotic (Akt and NFkB) proteins; however, chemoresistance remains a big challenge. Additional compounds with promising anticancer effects such as AKBA...