Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT

• المؤلفون الرئيسيون: SJ J. Diong (مؤلف), Aarti Jashnani (مؤلف), Andrew W. Drake (مؤلف), Christine Bee (مؤلف), Felix Findeisen (مؤلف), Gavin Dollinger (مؤلف), Feng Wang (مؤلف), Arvind Rajpal (مؤلف), Pavel Strop (مؤلف), Peter S. Lee (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

ABSTRACTThe clinical successes of immune checkpoint blockade have invigorated efforts to activate T cell-mediated responses against cancer. Targeting members of the PVR family, consisting of inhibitory receptors TIGIT, CD96, and CD112R, has been an active area of clinical investigation. In this stud...