TLR9-Dependent Activation by Inactivated Parapoxvirus Ovis in Murine Bone Marrow-Derived Dendritic Cells Is Associated with Specific Strain-Dependent Dendritic Cell Subsets

• Hauptverfasser: Yanqin Du (Verfasst von), Hang Sun (Verfasst von), Sonakshi Bhattacharjee (Verfasst von), Alexander Birkmann (Verfasst von), Ulf Dittmer (Verfasst von), Mengji Lu (Verfasst von)
• Format: Buch
• Veröffentlicht: Karger Publishers, 2024-06-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Introduction: Inactivated parapoxvirus ovis (iPPVO) exerts strong immunomodulatory effects on innate immune cells, making it an attractive therapeutic candidate. However, little is known about the signaling pathways that are involved in iPPVO-induced immune responses. Methods: In this study, we syst...