Protein Comparability Assessments and Potential Applicability of High Throughput Biophysical Methods and Data Visualization Tools to Compare Physical Stability Profiles

• Hlavní autoři: Mohammad A. Alsenaidy (Autor), Nishant K. eJain (Autor), Jae H. Kim (Autor), C. Russel Middaugh (Autor), David B. Volkin (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2014-03-01T00:00:00Z.
• Témata: article
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In this review, some of the challenges and opportunities encountered during protein comparability assessments are summarized with an emphasis on developing new analytical approaches to better monitor higher-order protein structures. Several case studies are presented using high throughput biophysica...