Protein Comparability Assessments and Potential Applicability of High Throughput Biophysical Methods and Data Visualization Tools to Compare Physical Stability Profiles

• Үндсэн зохиолчид: Mohammad A. Alsenaidy (Зохиогч), Nishant K. eJain (Зохиогч), Jae H. Kim (Зохиогч), C. Russel Middaugh (Зохиогч), David B. Volkin (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2014-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

In this review, some of the challenges and opportunities encountered during protein comparability assessments are summarized with an emphasis on developing new analytical approaches to better monitor higher-order protein structures. Several case studies are presented using high throughput biophysica...