Regulation of mycolactone, the Mycobacterium ulcerans toxin, depends on nutrient source.

• मुख्य लेखकों: Caroline Deshayes (लेखक), Shiva Kumar Angala (लेखक), Estelle Marion (लेखक), Irène Brandli (लेखक), Jérémie Babonneau (लेखक), Laurent Preisser (लेखक), Sara Eyangoh (लेखक), Yves Delneste (लेखक), Pierre Legras (लेखक), Chantal De Chastellier (लेखक), Timothy P Stinear (लेखक), Mary Jackson (लेखक), Laurent Marsollier (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2013-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

BACKGROUND: Mycobacterium ulcerans, a slow-growing environmental bacterium, is the etiologic agent of Buruli ulcer, a necrotic skin disease. Skin lesions are caused by mycolactone, the main virulence factor of M. ulcerans, with dermonecrotic (destruction of the skin and soft tissues) and immunosuppr...