Regulation of mycolactone, the Mycobacterium ulcerans toxin, depends on nutrient source.
BACKGROUND: Mycobacterium ulcerans, a slow-growing environmental bacterium, is the etiologic agent of Buruli ulcer, a necrotic skin disease. Skin lesions are caused by mycolactone, the main virulence factor of M. ulcerans, with dermonecrotic (destruction of the skin and soft tissues) and immunosuppr...
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Public Library of Science (PLoS),
2013-11-01T00:00:00Z.
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A1234.567 |
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