Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2

• Hoofdauteurs: Yi-Lin Chiu (Auteur), Yi-Ying Wu (Auteur), Robert B. Barndt (Auteur), Yee Hui Yeo (Auteur), Yu-Wen Lin (Auteur), Hou-Ping Sytwo (Auteur), Huan-Cheng Liu (Auteur), Yuan Xu (Auteur), Bailing Jia (Auteur), Jehng-Kang Wang (Auteur), Michael D. Johnson (Auteur), Chen-Yong Lin (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Matriptase is ectopically expressed in neoplastic B-cells, in which matriptase activity is enhanced by negligible expression of its endogenous inhibitor, hepatocyte growth factor activator inhibitor (HAI)-1. HAI-1, however, is also involved in matriptase synthesis and intracellular trafficking. The...