Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2

• मुख्य लेखकों: Yi-Lin Chiu (लेखक), Yi-Ying Wu (लेखक), Robert B. Barndt (लेखक), Yee Hui Yeo (लेखक), Yu-Wen Lin (लेखक), Hou-Ping Sytwo (लेखक), Huan-Cheng Liu (लेखक), Yuan Xu (लेखक), Bailing Jia (लेखक), Jehng-Kang Wang (लेखक), Michael D. Johnson (लेखक), Chen-Yong Lin (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Matriptase is ectopically expressed in neoplastic B-cells, in which matriptase activity is enhanced by negligible expression of its endogenous inhibitor, hepatocyte growth factor activator inhibitor (HAI)-1. HAI-1, however, is also involved in matriptase synthesis and intracellular trafficking. The...