Applying the estimand and target trial frameworks to external control analyses using observational data: a case study in the solid tumor setting

• Hoofdauteurs: Letizia Polito (Auteur), Qixing Liang (Auteur), Navdeep Pal (Auteur), Philani Mpofu (Auteur), Ahmed Sawas (Auteur), Olivier Humblet (Auteur), Kaspar Rufibach (Auteur), Dominik Heinzmann (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Introduction: In causal inference, the correct formulation of the scientific question of interest is a crucial step. The purpose of this study was to apply causal inference principles to external control analysis using observational data and illustrate the process to define the estimand attributes.M...