Applying the estimand and target trial frameworks to external control analyses using observational data: a case study in the solid tumor setting

• Váldodahkkit: Letizia Polito (Dahkki), Qixing Liang (Dahkki), Navdeep Pal (Dahkki), Philani Mpofu (Dahkki), Ahmed Sawas (Dahkki), Olivier Humblet (Dahkki), Kaspar Rufibach (Dahkki), Dominik Heinzmann (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Introduction: In causal inference, the correct formulation of the scientific question of interest is a crucial step. The purpose of this study was to apply causal inference principles to external control analysis using observational data and illustrate the process to define the estimand attributes.M...