Hyperphosphatemia-Induced Oxidant/Antioxidant Imbalance Impairs Vascular Relaxation and Induces Inflammation and Fibrosis in Old Mice

• Κύριοι συγγραφείς: Ana Asenjo-Bueno (Συγγραφέας), Elena Alcalde-Estévez (Συγγραφέας), Mariam El Assar (Συγγραφέας), Gemma Olmos (Συγγραφέας), Patricia Plaza (Συγγραφέας), Patricia Sosa (Συγγραφέας), Patricia Martínez-Miguel (Συγγραφέας), María Piedad Ruiz-Torres (Συγγραφέας), Susana López-Ongil (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2021-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Aging impairs vascular function, but the mechanisms involved are unknown. The aim of this study was to analyze whether aging-related hyperphosphatemia is implied in this effect by elucidating the role of oxidative stress. C57BL6 mice that were aged 5 months (young) and 24 months (old), receiving a s...