The Nitrobenzoxadiazole Derivative NBDHEX Behaves as <i>Plasmodium falciparum</i> Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity

This work describes the activity of 6-((7-nitrobenzo[<i>c</i>][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX) and of its newly identified carboxylic acid metabolite on the human malaria parasite <i>Plasmodium falciparum</i>. NBDHEX has been previously identified as a potent cy...

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Main Authors: Giulia Siciliano (Author), Veronica Di Paolo (Author), Dante Rotili (Author), Rossella Migale (Author), Francesca Pedini (Author), Marialuisa Casella (Author), Serena Camerini (Author), Daniele Dalzoppo (Author), Rob Henderson (Author), Tonnie Huijs (Author), Koen J. Dechering (Author), Antonello Mai (Author), Anna Maria Caccuri (Author), Marco Lalle (Author), Luigi Quintieri (Author), Pietro Alano (Author)
Format: Book
Published: MDPI AG, 2022-01-01T00:00:00Z.
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