The Nitrobenzoxadiazole Derivative NBDHEX Behaves as <i>Plasmodium falciparum</i> Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity

• Автори: Giulia Siciliano (Автор), Veronica Di Paolo (Автор), Dante Rotili (Автор), Rossella Migale (Автор), Francesca Pedini (Автор), Marialuisa Casella (Автор), Serena Camerini (Автор), Daniele Dalzoppo (Автор), Rob Henderson (Автор), Tonnie Huijs (Автор), Koen J. Dechering (Автор), Antonello Mai (Автор), Anna Maria Caccuri (Автор), Marco Lalle (Автор), Luigi Quintieri (Автор), Pietro Alano (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2022-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

This work describes the activity of 6-((7-nitrobenzo[<i>c</i>][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX) and of its newly identified carboxylic acid metabolite on the human malaria parasite <i>Plasmodium falciparum</i>. NBDHEX has been previously identified as a potent cy...