PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells

• Váldodahkkit: Isaac H. Caballero-Florán (Dahkki), Hernán Cortés (Dahkki), Fabiola V. Borbolla-Jiménez (Dahkki), Carla D. Florán-Hernández (Dahkki), María L. Del Prado-Audelo (Dahkki), Jonathan J. Magaña (Dahkki), Benjamín Florán (Dahkki), Gerardo Leyva-Gómez (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2023-05-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

This work proposes a combination of polyethylene glycol 400 (PEG) and trehalose as a surface modification approach to enhance PLGA-based nanoparticles as a drug carrier for neurons. PEG improves nanoparticles' hydrophilicity, and trehalose enhances the nanoparticle's cellular internalizati...