PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells

• Main Authors: Isaac H. Caballero-Florán (Author), Hernán Cortés (Author), Fabiola V. Borbolla-Jiménez (Author), Carla D. Florán-Hernández (Author), María L. Del Prado-Audelo (Author), Jonathan J. Magaña (Author), Benjamín Florán (Author), Gerardo Leyva-Gómez (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This work proposes a combination of polyethylene glycol 400 (PEG) and trehalose as a surface modification approach to enhance PLGA-based nanoparticles as a drug carrier for neurons. PEG improves nanoparticles' hydrophilicity, and trehalose enhances the nanoparticle's cellular internalizati...