PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells

• Glavni autori: Isaac H. Caballero-Florán (Autor), Hernán Cortés (Autor), Fabiola V. Borbolla-Jiménez (Autor), Carla D. Florán-Hernández (Autor), María L. Del Prado-Audelo (Autor), Jonathan J. Magaña (Autor), Benjamín Florán (Autor), Gerardo Leyva-Gómez (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2023-05-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

This work proposes a combination of polyethylene glycol 400 (PEG) and trehalose as a surface modification approach to enhance PLGA-based nanoparticles as a drug carrier for neurons. PEG improves nanoparticles' hydrophilicity, and trehalose enhances the nanoparticle's cellular internalizati...