A Negative Correlation Between Expression Profiles of Runt-Related Transcription Factor-2 and Cystine/Glutamate Antiporter xCT Subunit in Ovariectomized Mouse Bone

• Autori principali: Kyosuke Uno (Autore), Takeshi Takarada (Autore), Yukari Nakamura (Autore), Hiroyuki Fujita (Autore), Eiichi Hinoi (Autore), Yukio Yoneda (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2011-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

We have previously demonstrated that glutamate (Glu) suppresses cellular proliferation toward self-renewal through a mechanism associated with the depletion of intracellular GSH after promoting the retrograde operation of the bidirectional cystine/Glu antiporter in undifferentiated osteoblastic MC3T...