Safety, tolerability, and biomarkers of the treatment of mice with aerosolized toll-like receptor ligands
We have previously discovered a synergistically therapeutic combination of two Toll-like receptor (TLR) ligands, an oligodeoxynucleotide (ODN) and Pam2CSK4. Aerosolization of these ligands stimulates innate immunity within the lungs to prevent pneumonia from bacterial and viral pathogens. Here we ex...
Saved in:
Main Authors: | Victoria eAlfaro (Author), David L. Goldblatt (Author), Gabriella R. Valverde (Author), Mark eMunsell (Author), Lee J. Quinton (Author), Adam K. Walker (Author), Robert eDantzer (Author), Atul eVaradhachary (Author), Brenton L. Scott (Author), Scott E. Evans (Author), Michael J. Tuvim (Author), Burton F Dickey (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2014-02-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Epithelial immunomodulation by aerosolized Toll-like receptor agonists prevents allergic inflammation in airway mucosa in mice
by: David L. Goldblatt, et al.
Published: (2022) -
Antimicrobial Peptide Omiganan Enhances Interferon Responses to Endosomal Toll‐Like Receptor Ligands in Human Peripheral Blood Mononuclear Cells
by: Hendrika W. Grievink, et al.
Published: (2020) -
The Captain's Toll-Gate
by: Stockton, Frank R., 1834-1902; Stockton, Marian E. (Marian Edwards), -1906 [Contributor] -
The Expression and Functions of Toll-Like Receptors in Atherosclerosis
by: Jennifer E. Cole, et al.
Published: (2010) -
Toll-like receptors in systemic lupus erythematosus: potential for personalized treatment
by: Teja eCelhar, et al.
Published: (2014)