Comprehensive assessment of exposure to clozapine in association with side effects among patients with treatment-resistant schizophrenia: a population pharmacokinetic study

• Hauptverfasser: Nobuyuki Nomura (Verfasst von), Kohei Kitagawa (Verfasst von), Ryuhei So (Verfasst von), Fuminari Misawa (Verfasst von), Masafumi Kodama (Verfasst von), Hiroyoshi Takeuchi (Verfasst von), Robert Bies (Verfasst von), Thomas Straubinger (Verfasst von), Christopher Banker (Verfasst von), Yuya Mizuno (Verfasst von), Masaru Mimura (Verfasst von), Hiroyuki Uchida (Verfasst von)
• Format: Buch
• Veröffentlicht: SAGE Publishing, 2021-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Background: There have been scarce data on the distribution of clozapine concentrations in comparison with the recommended range (350-600 ng/ml) or their relationship with side effects among patients with treatment-resistant schizophrenia. Furthermore, no studies have assessed the association betwee...