Synthesis and evaluation of novel antifungal agents targeted to the plasma membrane H[+]-ATPase

• Հիմնական հեղինակներ: Dhruvnesh V Patel (Հեղինակ), J Paul Bassin (Հեղինակ), David G Griffiths (Հեղինակ)
• Ձևաչափ: Գիրք
• Հրապարակվել է: University of Huddersfield Press, 2018-07-01T00:00:00Z.
• Խորագրեր: article
• Առցանց հասանելիություն: Connect to this object online.

A library of dienones were synthesized as candidate antifungal agents. These compounds were screened against Saccharomyces cerevisiae and Candida albicans using macro-broth susceptibility assay. The dienones exhibited a broad range of inhibition against S. cerevisiae (0.2-99%) and C. albicans (0-99%...