Synthesis and evaluation of novel antifungal agents targeted to the plasma membrane H[+]-ATPase

A library of dienones were synthesized as candidate antifungal agents. These compounds were screened against Saccharomyces cerevisiae and Candida albicans using macro-broth susceptibility assay. The dienones exhibited a broad range of inhibition against S. cerevisiae (0.2-99%) and C. albicans (0-99%...

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Auteurs principaux: Dhruvnesh V Patel (Auteur), J Paul Bassin (Auteur), David G Griffiths (Auteur)
Format: Livre
Publié: University of Huddersfield Press, 2018-07-01T00:00:00Z.
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3rd Floor Main Library

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