Cholesterol esterification and p53-mediated tumor suppression

Many human cancers carry missense mutations in or deletions of the tumor protein 53 (TP53) tumor suppressor gene. TP53's product, p53 regulates many biological processes, including cell metabolism. Cholesterol is a key lipid needed for the maintenance of membrane function and tissue homeostasis...

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Bibliographic Details
Main Authors: Youjun Li (Author), Michael Karin (Author), Edward V. Prochownik (Author)
Format: Book
Published: Open Exploration Publishing Inc., 2023-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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