Discovery of a novel megakaryopoiesis enhancer, ingenol, promoting thrombopoiesis through PI3K-Akt signaling independent of thrombopoietin

• Asıl Yazarlar: Long Wang (Yazar), Ting Zhang (Yazar), Sha Liu (Yazar), Qi Mo (Yazar), Nan Jiang (Yazar), Qi Chen (Yazar), Jing Yang (Yazar), Yun-Wei Han (Yazar), Jian-Ping Chen (Yazar), Fei-Hong Huang (Yazar), Hua Li (Yazar), Jie Zhou (Yazar), Jie-Si Luo (Yazar), Jian-Ming Wu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2022-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Thrombocytopenia, a most common complication of radiotherapy and chemotherapy, is an important cause of morbidity and mortality in cancer patients. However, there are still no approved agents for the treatment of radiation- and chemotherapy-induced thrombocytopenia (RIT and CIT, respectively). In th...