Virus-like particle vaccines containing F or F and G proteins confer protection against respiratory syncytial virus without pulmonary inflammation in cotton rats

• Auteurs principaux: Hye Suk Hwang (Auteur), Ki-Hye Kim (Auteur), Youri Lee (Auteur), Young-Tae Lee (Auteur), Eun-Ju Ko (Auteur), SooJin Park (Auteur), Jong Seok Lee (Auteur), Byung-cheol Lee (Auteur), Young-Man Kwon (Auteur), Martin L. Moore (Auteur), Sang-Moo Kang (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2017-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Vaccine-enhanced disease has been a major obstacle in developing a safe vaccine against respiratory syncytial virus (RSV). This study demonstrates the immunogenicity, efficacy, and safety of virus-like particle (VLP) vaccines containing RSV F (F VLP), G (G VLP), or F and G proteins (FG VLP) in cotto...