Virus-like particle vaccines containing F or F and G proteins confer protection against respiratory syncytial virus without pulmonary inflammation in cotton rats

• Main Authors: Hye Suk Hwang (Author), Ki-Hye Kim (Author), Youri Lee (Author), Young-Tae Lee (Author), Eun-Ju Ko (Author), SooJin Park (Author), Jong Seok Lee (Author), Byung-cheol Lee (Author), Young-Man Kwon (Author), Martin L. Moore (Author), Sang-Moo Kang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vaccine-enhanced disease has been a major obstacle in developing a safe vaccine against respiratory syncytial virus (RSV). This study demonstrates the immunogenicity, efficacy, and safety of virus-like particle (VLP) vaccines containing RSV F (F VLP), G (G VLP), or F and G proteins (FG VLP) in cotto...