Virus-like particle vaccines containing F or F and G proteins confer protection against respiratory syncytial virus without pulmonary inflammation in cotton rats

• Главные авторы: Hye Suk Hwang (Автор), Ki-Hye Kim (Автор), Youri Lee (Автор), Young-Tae Lee (Автор), Eun-Ju Ko (Автор), SooJin Park (Автор), Jong Seok Lee (Автор), Byung-cheol Lee (Автор), Young-Man Kwon (Автор), Martin L. Moore (Автор), Sang-Moo Kang (Автор)
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• Опубликовано: Taylor & Francis Group, 2017-05-01T00:00:00Z.
• Предметы: article
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Vaccine-enhanced disease has been a major obstacle in developing a safe vaccine against respiratory syncytial virus (RSV). This study demonstrates the immunogenicity, efficacy, and safety of virus-like particle (VLP) vaccines containing RSV F (F VLP), G (G VLP), or F and G proteins (FG VLP) in cotto...