Cylindromatosis (CYLD), a Deubiquitinase, Attenuates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells

• Váldodahkkit: Tadaatsu Imaizumi (Dahkki), Ryo Hayakari (Dahkki), Shojiro Watanabe (Dahkki), Tomomi Aizawa (Dahkki), Tomoh Matsumiya (Dahkki), Hidemi Yoshida (Dahkki), Kazushi Tsuruga (Dahkki), Shogo Kawaguchi (Dahkki), Hiroshi Tanaka (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Karger Publishers, 2017-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background/Aims: Cylindromatosis (CYLD), a deubiquitinase, negatively regulates nuclear factor-κB in various cells. However, its potential roles in glomerular inflammation remain unclear. Because the activation of the Toll-like receptor 3 (TLR3)/type I interferon (IFN) pathways plays a pivotal role...