Cylindromatosis (CYLD), a Deubiquitinase, Attenuates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells

• मुख्य लेखकों: Tadaatsu Imaizumi (लेखक), Ryo Hayakari (लेखक), Shojiro Watanabe (लेखक), Tomomi Aizawa (लेखक), Tomoh Matsumiya (लेखक), Hidemi Yoshida (लेखक), Kazushi Tsuruga (लेखक), Shogo Kawaguchi (लेखक), Hiroshi Tanaka (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Karger Publishers, 2017-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background/Aims: Cylindromatosis (CYLD), a deubiquitinase, negatively regulates nuclear factor-κB in various cells. However, its potential roles in glomerular inflammation remain unclear. Because the activation of the Toll-like receptor 3 (TLR3)/type I interferon (IFN) pathways plays a pivotal role...