Magnoflorine Suppresses MAPK and NF-κB Signaling to Prevent Inflammatory Osteolysis Induced by Titanium Particles In Vivo and Osteoclastogenesis via RANKL In Vitro

• Asıl Yazarlar: Zhenyu Sun (Yazar), Junkai Zeng (Yazar), Wenjuan Wang (Yazar), Xinlin Jia (Yazar), Qiang Wu (Yazar), Degang Yu (Yazar), Yuanqing Mao (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2020-04-01T00:00:00Z.
• Konular: article
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Wear particles that detach from the surface of prostheses induce excessive activation of osteoclast and immoderate release of inflammatory cytokines that lead to peri-implant osteolysis and aseptic loosening. In this work, we investigated whether magnoflorine, a quaternary aporphine alkaloid extract...