Pharmacological inhibition of ALCAT1 mitigates amyotrophic lateral sclerosis by attenuating SOD1 protein aggregation

Objective: Mutations in the copper-zinc superoxide dismutase (SOD1) gene cause familial amyotrophic lateral sclerosis (ALS), a progressive fatal neuromuscular disease characterized by motor neurons death and severe skeletal muscle degeneration. However, there is no effective treatment for this debil...

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Main Authors: Xueling Liu (Author), Jun Zhang (Author), Jie Li (Author), Chengjie Song (Author), Yuguang Shi (Author)
Format: Book
Published: Elsevier, 2022-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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