Increasing the biorelevance of simulated intestinal fluids for better predictions of drug equilibrium solubility in the fasted upper small intestine

To date the importance of luminal species other than bile salts and phosphatidylcholine on drug equilibrium solubility in the fasted upper small intestine has not been evaluated. In this communication the importance of fatty acids, cholesterol, and proteins on solubility of four model lipophilic com...

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Váldodahkkit: Nikolaos Koumandrakis (Dahkki), Maria Vertzoni (Dahkki), Christos Reppas (Dahkki)
Materiálatiipa: Girji
Almmustuhtton: International Association of Physical Chemists (IAPC), 2014-07-01T00:00:00Z.
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3rd Floor Main Library

oažžasuvvan: 3rd Floor Main Library
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