Understanding the structure-property relationship of bispecific monoclonal antibodies with Fc site-specific substitutions

• Главные авторы: Bo Zhao (Автор), Yunlong Zhao (Автор), Stephanie Adaniya (Автор), Yue Fu (Автор), Youmi Moon (Автор), Justin Heftel (Автор), Shuzhen Chen (Автор), Hui Xiao (Автор), Ning Li (Автор)
• Формат: ‌
• Опубликовано: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Предметы: article
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ABSTRACTDevelopment of novel bispecific antibody (bsAb) platforms offers unprecedented opportunities for a wide variety of therapeutic applications. However, the expression and manufacturing of bsAbs with desired structures can be challenging. Owing to the uniqueness of each bsAb platform, more comp...