Understanding the structure-property relationship of bispecific monoclonal antibodies with Fc site-specific substitutions

• 主要な著者: Bo Zhao (著者), Yunlong Zhao (著者), Stephanie Adaniya (著者), Yue Fu (著者), Youmi Moon (著者), Justin Heftel (著者), Shuzhen Chen (著者), Hui Xiao (著者), Ning Li (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

ABSTRACTDevelopment of novel bispecific antibody (bsAb) platforms offers unprecedented opportunities for a wide variety of therapeutic applications. However, the expression and manufacturing of bsAbs with desired structures can be challenging. Owing to the uniqueness of each bsAb platform, more comp...