Adiposity is associated with widespread transcriptional changes and downregulation of longevity pathways in aged skeletal muscle

• Үндсэн зохиолчид: Mark A. Burton (Зохиогч), Elie Antoun (Зохиогч), Emma S. Garratt (Зохиогч), Leo Westbury (Зохиогч), Alica Baczynska (Зохиогч), Elaine M. Dennison (Зохиогч), Nicholas C. Harvey (Зохиогч), Cyrus Cooper (Зохиогч), Harnish P. Patel (Зохиогч), Keith M. Godfrey (Зохиогч), Karen A. Lillycrop (Зохиогч), EpiGen Global Research Consortium (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Wiley, 2023-08-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Background Amongst healthy older people, a number of correlates of impaired skeletal muscle mass and function have been defined. Although the prevalence of obesity is increasing markedly in this age group, information is sparse about the particular impacts of obesity on ageing skeletal musc...