MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo

• मुख्य लेखकों: Karolin Walter (लेखक), Kanishka Tiwary (लेखक), Marija Trajkovic-Arsic (लेखक), Ana Hidalgo-Sastre (लेखक), Laura Dierichs (लेखक), Sven T. Liffers (लेखक), Jiangning Gu (लेखक), Johann Gout (लेखक), Lucas-Alexander Schulte (लेखक), Jan Münch (लेखक), Thomas Seufferlein (लेखक), Bruno Sainz (लेखक), Jens T. Siveke (लेखक), Eva Rodriguez-Aznar (लेखक), Patrick C. Hermann (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2019-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Pancreatic ductal adenocarcinoma (PDAC) remains a devastating disease with a very poor prognosis. At the same time, its incidence is on the rise, and PDAC is expected to become the second leading cause of cancer-related death by 2030. Despite extensive work on new therapeutic approaches, the median...