MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo

• Главные авторы: Karolin Walter (Автор), Kanishka Tiwary (Автор), Marija Trajkovic-Arsic (Автор), Ana Hidalgo-Sastre (Автор), Laura Dierichs (Автор), Sven T. Liffers (Автор), Jiangning Gu (Автор), Johann Gout (Автор), Lucas-Alexander Schulte (Автор), Jan Münch (Автор), Thomas Seufferlein (Автор), Bruno Sainz (Автор), Jens T. Siveke (Автор), Eva Rodriguez-Aznar (Автор), Patrick C. Hermann (Автор)
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• Опубликовано: Hindawi Limited, 2019-01-01T00:00:00Z.
• Предметы: article
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Pancreatic ductal adenocarcinoma (PDAC) remains a devastating disease with a very poor prognosis. At the same time, its incidence is on the rise, and PDAC is expected to become the second leading cause of cancer-related death by 2030. Despite extensive work on new therapeutic approaches, the median...