Leishmania specific CD4 T cells release IFNγ that limits parasite replication in patients with visceral leishmaniasis.

• Asıl Yazarlar: Rajiv Kumar (Yazar), Neetu Singh (Yazar), Shalini Gautam (Yazar), Om Prakash Singh (Yazar), Kamlesh Gidwani (Yazar), Madhukar Rai (Yazar), David Sacks (Yazar), Shyam Sundar (Yazar), Susanne Nylén (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Visceral leishmaniasis (VL) is associated with increased circulating levels of multiple pro-inflammatory cytokines and chemokines, including IL-12, IFNγ, and TNFα, and elevated expression of IFNγ mRNA in lesional tissue such as the spleen and bone marrow. However, an immunological feature of VL pati...