Icariin Activates Autophagy via Down-Regulation of the NF-κB Signaling-Mediated Apoptosis in Chondrocytes

• Main Authors: Bobin Mi (Author), Junqing Wang (Author), Yi Liu (Author), Jing Liu (Author), Liangcong Hu (Author), Adriana C. Panayi (Author), Guohui Liu (Author), Wu Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) is a common chronic and degenerative joint condition that is mainly characterized by cartilage degradation, osteophyte formation, and joint stiffness. The NF-κB signaling pathway in inflammation, autophagy, and apoptosis plays a prominent role in the progression of OA. Icariin, a...