Icariin Activates Autophagy via Down-Regulation of the NF-κB Signaling-Mediated Apoptosis in Chondrocytes

• Hoofdauteurs: Bobin Mi (Auteur), Junqing Wang (Auteur), Yi Liu (Auteur), Jing Liu (Auteur), Liangcong Hu (Auteur), Adriana C. Panayi (Auteur), Guohui Liu (Auteur), Wu Zhou (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Osteoarthritis (OA) is a common chronic and degenerative joint condition that is mainly characterized by cartilage degradation, osteophyte formation, and joint stiffness. The NF-κB signaling pathway in inflammation, autophagy, and apoptosis plays a prominent role in the progression of OA. Icariin, a...