Trimethylamine-N-Oxide Aggravates Kidney Injury via Activation of p38/MAPK Signaling and Upregulation of HuR

• मुख्य लेखकों: Yunshi Lai (लेखक), Haie Tang (लेखक), Xinrong Zhang (लेखक), Zhanmei Zhou (लेखक), Miaomiao Zhou (लेखक), Zheng Hu (लेखक), Fengxin Zhu (लेखक), Lei Zhang (लेखक), Jing Nie (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Karger Publishers, 2021-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Trimethylamine-N-oxide (TMAO) is an intestinal metabolic toxin, which is produced by gut flora via metabolizing high-choline foods. TMAO is known to increase the risk of atherosclerosis and cardiovascular events in chronic kidney disease (CKD) patients. Objectives: The objective of this...