Trimethylamine-N-Oxide Aggravates Kidney Injury via Activation of p38/MAPK Signaling and Upregulation of HuR

• Hoofdauteurs: Yunshi Lai (Auteur), Haie Tang (Auteur), Xinrong Zhang (Auteur), Zhanmei Zhou (Auteur), Miaomiao Zhou (Auteur), Zheng Hu (Auteur), Fengxin Zhu (Auteur), Lei Zhang (Auteur), Jing Nie (Auteur)
• Formaat: Boek
• Gepubliceerd in: Karger Publishers, 2021-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background: Trimethylamine-N-oxide (TMAO) is an intestinal metabolic toxin, which is produced by gut flora via metabolizing high-choline foods. TMAO is known to increase the risk of atherosclerosis and cardiovascular events in chronic kidney disease (CKD) patients. Objectives: The objective of this...