Discoidin domain receptor 1-deletion ameliorates fibrosis and promotes adipose tissue beiging, brown fat activity, and increased metabolic rate in a mouse model of cardiometabolic disease

Discoidin domain receptor 1-deletion ameliorates fibrosis and promotes adipose tissue beiging, brown fat activity, and increased metabolic rate in a mouse model of cardiometabolic disease

Objective: Discoidin domain receptor 1 (DDR1) is a collagen binding receptor tyrosine kinase implicated in atherosclerosis, fibrosis, and cancer. Our previous research showed that DDR1 could regulate smooth muscle cell trans-differentiation, fibrosis and calcification in the vascular system in cardi...

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Main Authors: Marsel Lino (Author), David Ngai (Author), Alison Liu (Author), Amanda Mohabeer (Author), Cameron Harper (Author), Laura-lee Caruso (Author), Stephanie A. Schroer (Author), Fred Fu (Author), Trevor McKee (Author), Adria Giacca (Author), Minna Woo (Author), Michelle P. Bendeck (Author)
Format: Book
Published: Elsevier, 2020-09-01T00:00:00Z.
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