Discoidin domain receptor 1-deletion ameliorates fibrosis and promotes adipose tissue beiging, brown fat activity, and increased metabolic rate in a mouse model of cardiometabolic disease

• প্রধান লেখক: Marsel Lino (লেখক), David Ngai (লেখক), Alison Liu (লেখক), Amanda Mohabeer (লেখক), Cameron Harper (লেখক), Laura-lee Caruso (লেখক), Stephanie A. Schroer (লেখক), Fred Fu (লেখক), Trevor McKee (লেখক), Adria Giacca (লেখক), Minna Woo (লেখক), Michelle P. Bendeck (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2020-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Objective: Discoidin domain receptor 1 (DDR1) is a collagen binding receptor tyrosine kinase implicated in atherosclerosis, fibrosis, and cancer. Our previous research showed that DDR1 could regulate smooth muscle cell trans-differentiation, fibrosis and calcification in the vascular system in cardi...