Off- and on-target effects of genome editing in mouse embryos

Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas-based genome editing technology has enabled manipulation of the embryonic genome. Unbiased whole genome sequencing comparing parents to progeny has revealed that the rate of Cas9-induced mutagenesis in mouse embryos is indistingu...

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Bibliographic Details
Main Authors: Shinya AYABE (Author), Kenichi NAKASHIMA (Author), Atsushi YOSHIKI (Author)
Format: Book
Published: The Society for Reproduction and Development, 2018-12-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available