Original Fluorescent Ligand-Based Assays Open New Perspectives in G-Protein Coupled Receptor Drug Screening

• 主要な著者: Thierry Durroux (著者), Jurriaan M. Zwier (著者), Eric Trinquet (著者), Orestis Faklaris (著者), Martin Cottet (著者), Jean-Philippe Pin (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2011-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The identification of new drugs exhibiting reduced adverse side-effects constitutes a great challenge for the next decade. Various steps are needed to screen for good ligand candidates and one of them is the evaluation of their binding properties. New strategies based on fluorescence measurement con...