Original Fluorescent Ligand-Based Assays Open New Perspectives in G-Protein Coupled Receptor Drug Screening

• Main Authors: Thierry Durroux (Author), Jurriaan M. Zwier (Author), Eric Trinquet (Author), Orestis Faklaris (Author), Martin Cottet (Author), Jean-Philippe Pin (Author)
• Format: Book
• Published: MDPI AG, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The identification of new drugs exhibiting reduced adverse side-effects constitutes a great challenge for the next decade. Various steps are needed to screen for good ligand candidates and one of them is the evaluation of their binding properties. New strategies based on fluorescence measurement con...