PU-H71 (NSC 750424): a molecular masterpiece that targets HSP90 in cancer and beyond

• Päätekijät: Sameh Saber (Tekijä), Rasha Abdelhady (Tekijä), Mai A. Elhemely (Tekijä), Elsayed A. Elmorsy (Tekijä), Rabab S. Hamad (Tekijä), Mustafa Ahmed Abdel-Reheim (Tekijä), Attalla F. El-kott (Tekijä), Mohammed A. AlShehri (Tekijä), Kareem Morsy (Tekijä), Ali S. AlSheri (Tekijä), Mahmoud E. Youssef (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Heat shock protein 90 (HSP90) is a pivotal molecular chaperone with multifaceted roles in cellular health and disease. Herein, we explore how HSP90 orchestrates cellular stress responses, particularly through its partnership with heat shock factor 1 (HSF-1). PU-H71, a selective inhibitor of HSP90, d...