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Vincristine Promotes Transdifferentiation of Fibroblasts Into Myofibroblasts via P38 and ERK Signal Pathways

Background: Vincristine (VCR) is used in the clinic as an anti-tumor drug. VCR can cause pulmonary fibrosis (PF), leading to respiratory failure. The transformation of fibroblasts into myofibroblasts may play a key role in PF. The present study attempted to reveal the molecular mechanism of VCR-indu...

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Main Authors: Hui Xu (Author), Jingwen Yang (Author), Mengyun Tu (Author), Jie Weng (Author), Mengying Xie (Author), Zhiliang Zhou (Author), Peisen Zhou (Author), Liang Wang (Author), Chan Chen (Author), Zhiyi Wang (Author)
Format: Book
Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
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