Residue-resolved insights into the stabilization of therapeutic proteins by excipients: A case study of two monoclonal antibodies with arginine and glutamate

Protein formulation development relies on the selection of excipients that inhibit protein-protein interactions preventing aggregation. Empirical strategies involve screening many excipient and buffer combinations by physicochemical characterization using forced degradation or temperature-induced st...

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Auteurs principaux: Tobias M. Prass (Auteur), Patrick Garidel (Auteur), Lars V. Schäfer (Auteur), Michaela Blech (Auteur)
Format: Livre
Publié: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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