The essential role of YAP in ERα36-mediated proliferation and the epithelial-mesenchymal transition in MCF-7 breast cancer cells

• 主要な著者: Miso Park (著者), Seung Hyun Lee (著者), Quyen Thu Bui (著者), Young-Mi Kim (著者), Keon Wook Kang (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Purpose: Most breast cancers are hormone-receptor-positive, and thus the first-line therapy for them is an anti-estrogen medication such as tamoxifen. If metastasis occurs or resistance to tamoxifen develops, the 5-year survival rates for breast cancer patients significantly decrease. Hence, a bette...