The essential role of YAP in ERα36-mediated proliferation and the epithelial-mesenchymal transition in MCF-7 breast cancer cells

• Główni autorzy: Miso Park (Autor), Seung Hyun Lee (Autor), Quyen Thu Bui (Autor), Young-Mi Kim (Autor), Keon Wook Kang (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Purpose: Most breast cancers are hormone-receptor-positive, and thus the first-line therapy for them is an anti-estrogen medication such as tamoxifen. If metastasis occurs or resistance to tamoxifen develops, the 5-year survival rates for breast cancer patients significantly decrease. Hence, a bette...