Discovery of Polyphenolic Natural Products as SARS-CoV-2 M^pro Inhibitors for COVID-19

• Main Authors: Nadine Krüger (Author), Thales Kronenberger (Author), Hang Xie (Author), Cheila Rocha (Author), Stefan Pöhlmann (Author), Haixia Su (Author), Yechun Xu (Author), Stefan A. Laufer (Author), Thanigaimalai Pillaiyar (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has forced the development of direct-acting antiviral drugs due to the coronavirus disease 2019 (COVID-19) pandemic. The main protease of SARS-CoV-2 is a crucial enzyme that breaks down polyproteins synthesized from the viral RNA, maki...