Discovery of Polyphenolic Natural Products as SARS-CoV-2 M^pro Inhibitors for COVID-19

• Главные авторы: Nadine Krüger (Автор), Thales Kronenberger (Автор), Hang Xie (Автор), Cheila Rocha (Автор), Stefan Pöhlmann (Автор), Haixia Su (Автор), Yechun Xu (Автор), Stefan A. Laufer (Автор), Thanigaimalai Pillaiyar (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2023-01-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has forced the development of direct-acting antiviral drugs due to the coronavirus disease 2019 (COVID-19) pandemic. The main protease of SARS-CoV-2 is a crucial enzyme that breaks down polyproteins synthesized from the viral RNA, maki...