TMI-1, TNF-α-Converting Enzyme Inhibitor, Protects Against Paclitaxel-Induced Neurotoxicity in the DRG Neuronal Cells In Vitro

• 主要な著者: Yesul Kim (著者), Young-Hoon Jung (著者), Seung-Bin Park (著者), Heekee Kim (著者), Jae-young Kwon (著者), Hae-kyu Kim (著者), Hyeon-Jeong Lee (著者), Soeun Jeon (著者), Eunsoo Kim (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background: Chemotherapy-induced peripheral neuropathy (CIPN) negatively impacts cancer survivors' quality of life and is challenging to treat with existing drugs for neuropathic pain. TNF-α is known to potentiate TRPV1 activity, which contributes to CIPN. Here, we assessed the role of TMI-1, a...