Open channel block of Kv1.5 channels by HMQ1611

• Päätekijät: Chao Dong (Tekijä), Jiawei Li (Tekijä), Weiguang Ding (Tekijä), Rika Ueda (Tekijä), Xiaolu Xie (Tekijä), Jie Wu (Tekijä), Hiroshi Matsuura (Tekijä), Minoru Horie (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Kv1.5 channels conduct the ultra-rapid delayed rectifier potassium current (IKur). Pharmacological blockade of human Kv1.5 (hKv1.5) has been regarded as an effective treatment of re-entrant based atrial fibrillation, because Kv1.5 is highly expressed in human cardiac atria but scarcely in ventricles...