Open channel block of Kv1.5 channels by HMQ1611
Kv1.5 channels conduct the ultra-rapid delayed rectifier potassium current (IKur). Pharmacological blockade of human Kv1.5 (hKv1.5) has been regarded as an effective treatment of re-entrant based atrial fibrillation, because Kv1.5 is highly expressed in human cardiac atria but scarcely in ventricles...
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Frontiers Media S.A.,
2022-09-01T00:00:00Z.
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