Open channel block of Kv1.5 channels by HMQ1611

• Váldodahkkit: Chao Dong (Dahkki), Jiawei Li (Dahkki), Weiguang Ding (Dahkki), Rika Ueda (Dahkki), Xiaolu Xie (Dahkki), Jie Wu (Dahkki), Hiroshi Matsuura (Dahkki), Minoru Horie (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Kv1.5 channels conduct the ultra-rapid delayed rectifier potassium current (IKur). Pharmacological blockade of human Kv1.5 (hKv1.5) has been regarded as an effective treatment of re-entrant based atrial fibrillation, because Kv1.5 is highly expressed in human cardiac atria but scarcely in ventricles...